Comprehensive cytogenetic study by spectral karyotyping on blastic natural killer cell leukemia/lymphoma
نویسندگان
چکیده
منابع مشابه
Primary cutaneous blastic natural killer cell lymphoma.
Sir, Blastic natural killer-cell lymphoma, also called “agranular CD4+ CD56+ haematodermic neoplasm” is an uncommon type of tumour, which is included in the new World Health Organization (WHO) classification as a malignancy derived from natural killer (NK) cells. It is very aggressive, affecting many organs, and skin involvement is highly characteristic. Several origins have been proposed, but ...
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متن کاملBlastic natural killer (NK) cell leukemia (agranular CD4+CD56+ leukemia).
Blastic NK cell lymphoma is a rare hematolymphoid neoplasm. This report illustrates an unusual presentation of this entity, namely as a primary leukemia, but without skin lesions.
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T/natural killer-cell lymphomas belong to a heterogeneous group of non-Hodgkin lymphomas with predominant extranodal, often cutaneous, manifestations. In contrast to B- and T-cell lymphomas, T/NK-cell lymphomas were only recently regarded as a distinct entity. These rather aggressive malignancies arise from cytotoxic T cells, NK-cells or NK-like T cells, which share several phenotypic and funct...
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We investigated relationships between DNA copy number aberrations and chromosomal structural rearrangements in 11 different cell lines derived from oral squamous cell carcinoma (OSCC) by comparative genomic hybridization (CGH), spectral karyotyping (SKY), and fluorescence in situ hybridization (FISH). CGH frequently showed recurrent chromosomal gains of 5p, 20q12, 8q23 approximately qter, 20p11...
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ژورنال
عنوان ژورنال: American Journal of Hematology
سال: 2002
ISSN: 0361-8609,1096-8652
DOI: 10.1002/ajh.10063.abs